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Defining the roles of genetic drivers of uveal melanoma with cell-based and Drosophila models
Institut Curie, AmphitheaterHélène Martel-Massignac (BDD), 11 rue Pierre et Marie Curie, Paris The seminar will also be broadcasted online viaTeams*
Uveal melanoma is the most common eye cancer in adults with a set of highly characteristic genetic alterations. We identified mutations in the BAP1 (BRCA1 Associated Protein 1) gene in uveal melanomas with high likelihood of metastasis and recurrent mutations in the splicing factor SF3B1 with less chance of metastasis.